LYMPHOID NEOPLASIA HLA-DP genetic variation, proxies for early life immune modulation and childhood acute lymphoblastic leukemia risk
نویسندگان
چکیده
1School of Public Health, University of California, Berkeley, CA; 2Center for Clinical Epidemiology, St Luke’s Life Science Institute, Tokyo, Japan; 3Yale University School of Medicine, New Haven, CT; 4Genetic Epidemiology and Genomics Laboratory, University of California, Berkeley, CA; 5Laboratory for Molecular and Neuroepidemiology, University of California, San Francisco, CA; 6Cancer Immunogenetics Group, University of Manchester, St Mary’s Hospital, Manchester, United Kingdom; 7Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France; 8Division of Pediatric Hematology/Oncology/BMT, Stanford University School of Medicine, Stanford, CA; 9Roche Molecular Systems Inc, Pleasanton, CA; and 10Center for Genetics, Children’s Hospital Oakland Research Institute, CA
منابع مشابه
HLA-DP genetic variation, proxies for early life immune modulation and childhood acute lymphoblastic leukemia risk.
The human leukocyte antigen (HLA) genes are candidate genetic susceptibility loci for childhood acute lymphoblastic leukemia (ALL). We examined the effect of HLA-DP genetic variation on risk and evaluated its potential interaction with 4 proxies for early immune modulation, including measures of infectious exposures in infancy (presence of older siblings, daycare attendance, ear infections) and...
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